Precision medicine promises to provide better matches between treatments and groups of patients who have a disease and who show a set of specific traits. Better matches help ensure that a drug would be given to those who would benefit most and not be given to those who would either not be helped or would be harmed by it. A lot of attention in precision medicine focuses on powerful machine learning algorithms that can identify new sub-populations of patient groups. However, the results depend on the input data. The input data is defined by which patients are included. …

There is a popular proverb that says: “if you want to go fast, go alone. If you want to go far, go together.”

At Benevolent, this rings true in all that we do. We want to go far. Envisioning a world where no disease goes untreated is a bold ambition, and not something we can achieve alone. We believe that when working together, amazing things can happen.

As Director of Talent Acquisition and Development, I am responsible for sourcing the right mix of experience, skill and passion to bring into our team. Our squads are eclectic and diverse, filled with an extraordinary mix of scientific and technical expertise. Though they hail from seemingly disparate fields, all of which focus on tackling exceptionally hard…

BenevolentAI researchers
BenevolentAI researchers

Humans are social animals, a fact we are reminded of daily as we hunker down in our socially distant cocoons due to the COVID-19 crisis, while we are forced to share zoom drinks and virtual birthdays with friends and family, desperate to stay connected.

We all sit somewhere on a spectrum of sociability — whether you’re an introvert perfectly happy in your own company, or an extroverted social butterfly constantly in communication with swathes of people by a myriad of media. Everyone needs interactions with other people, be it for energy, motivation, support, information, reassurance. So why would developing software be any different when humans are going about it?

For anyone who has ever developed a software application of any sort, I put this question to you: what do you spend most of your time doing? Is it typing reams of code like…

BenevolentAI hands reaching
BenevolentAI hands reaching

While scientists scramble to identify potential treatments and develop a vaccination to treat the physical symptoms of COVID-19, the rest of society is faced with coping with the secondary effects of the virus — the mental toll of isolation, economic instability or family crises.

On top of this, with the internet awash with news of COVID-19, our phones abuzz with continual updates on the latest government orders and infection spikes, it is often difficult to switch off from the seemingly relentless background hum of worry. Rarely has Mental Health Week been so directly relevant to so many. However, in this struggle we possess a powerful and potent antidote: kindness.

Multiple studies have proven that kindness really does matter. From a personal perspective, kindness can help improve feelings of happiness and reduce stress and improve emotional wellbeing ( ref). It has also been demonstrated that…

BenevolentAI woman doing yoga
BenevolentAI woman doing yoga

Yoga means much more than simply doing impressive postures — it can help maintain or improve mental health too.

At Benevolent, Marton and Francesca are both Senior Data Scientists, Marton specialises in Cheminformatics, and Francesca in Bioinformatics. On top of being professional scientists, they are also professional yogis who have continued to teach weekly remote yoga classes to our Benevolent team throughout lockdown. In this special Mental Health Awareness Week blog, they discuss how these seemingly disparate fields interact, and evaluate the science behind the effect of yoga on mental health.

What do you know of the history of yoga?

Márton Vass. Yoga is a tradition that goes back thousands of years. We don’t know when people started practicing…

BenevolentAI Women speaking about equality
BenevolentAI Women speaking about equality

To celebrate International Women’s Day we hosted a fireside chat in London with four of our inspiring female colleagues to learn more about their experiences, successes and the barriers or challenges they’ve faced as a woman in a largely male dominated industry.

The Q&A was driven by questions submitted by our team via an anonymous poll, which opened the floor to an open and honest discussion around some of the most pressing issues facing women in STEM.

What is the biggest challenge you had to face in your career so far?

Trecilla: My challenges relate to juggling my career, family, and the stereotypes associated with being a working parent. It was incredibly difficult to make the decision to go back to work when my daughter was 4 months old. Firstly, because I felt guilty about leaving my child in a nursery. Secondly, because I also felt guilty about being happy about going back to work.

How historically neglecting sex differences has impacted women’s health.

Sex differences have historically been neglected in clinical research, design and practice. To mark International Women’s Day, we explored how this ‘one size fits all’ approach to medical research and treatment impacts women’s health.

Men and women are different in several ways in terms of their biological makeup, and it has been long known that the expression of genes on X and Y chromosomes have a profound effect on health and well-being. Difference in sex not only contributes to the physiological and anatomical variations but also influences the behavioural traits and disease risks. For instance, most autoimmune diseases occur more frequently in women while hypertension is observed more frequently in young men than in young women. …

BenevolentAI- expert researchers
BenevolentAI- expert researchers

It is well documented that the lack of representation in biomedical research is leading to a data gap that can no longer be overlooked if we are to avoid exacerbating existing health inequalities in the age of digital health.

Advances in machine learning (ML) techniques are allowing the scientific community to unlock the potential of biomedical data and extract valuable insights. Yet amidst the hope sits a certain uncomfortable reality: not everyone is set to benefit from these advances. At the heart of innovation in healthcare lies the datasets used to train the algorithms, such as data from scientific literature, clinical trials, omics, and patient real world data. These datasets are the lifeblood of new technologies, and are extremely meaningful. Yet, they have significant shortcomings, since the majority of medical research is conducted on white and predominantly male populations…

BenevolentAI- digital rendering of the human brain
BenevolentAI- digital rendering of the human brain

Earlier this month we announced our partnership with the University of California San Diego, supported by the Angioma Alliance charity, to collaborate on a new approach to develop non-invasive therapeutic treatments for cerebral cavernous malformations (CCM).

This week we caught up with Andrea Taddei, Senior Principal Scientist at BenevolentAI, who shared insight into his work to use AI to identify new targets associated with this rare and complex disease for which the only current treatment option is brain surgery.

At Benevolent, Andrea leads a multidisciplinary team on several drug discovery programmes from target identification through application of artificial intelligence platforms to selection of candidates for chemistry optimisation. …

BenevolentAI- Text “AI uncovers relationships between diseases, symptoms, drugs, a patient’s response to treatment and more”
BenevolentAI- Text “AI uncovers relationships between diseases, symptoms, drugs, a patient’s response to treatment and more”

Today we’re honoured to be named as one of MIT Technology Review’s top 10 breakthrough technologies of 2020.

The prestigious list, curated by MIT Technology Review’s editorial team, is subject to meticulous research and a rigorous process of elimination in order to identify the ten most important technology breakthroughs of the year which are expected to have the biggest impact on human life in the decade ahead.

AI-enabled molecules feature as one of the technologies on the 2020 list, where we’re proud to be recognised for our work in AI-driven chemical design. …

BenevolentAI

BenevolentAI is the global leader in the development and application of #artificialintelligence ('AI") for scientific innovation. www.benevolent.com

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